Publications

British journal of pharmacology

Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdr 1a P-glycoprotein.

The Journal of experimental medicine

Domains of the TCR beta-chain required for early thymocyte development.

Journal of pharmaceutical sciences

Systematic study on the chemical stability of the prodrug antitumor agent carzelesin (U-80,244).

The Journal of cell biology

Direct vesicular transport of MHC class II molecules from lysosomal structures to the cell surface.

The Journal of biological chemistry

mUBC9, a novel adenovirus E1A-interacting protein that complements a yeast cell cycle defect.

18-10-1996

The Journal of neuroscience : the official journal of the Society for Neuroscience

Peripheral neuropathy in mice transgenic for a human MDR3 P-glycoprotein mini-gene.

15-10-1996

Pharmacy world & science : PWS

Etoposide phosphate, the water soluble prodrug of etoposide.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

The European Organization for Research and Treatment of Cancer breast cancer-specific quality-of-life questionnaire module: first results from a three-country field study.

European journal of biochemistry

The role of the cytoplasmic domain of alpha 6 integrin in the assembly and function of alpha 6 beta 1 and alpha 6 beta 4.

Current opinion in cell biology

Hemidesmosomes: roles in adhesion, signaling and human diseases.

Seminars in cancer biology

Complementation tagging of cooperating oncogenes in knockout mice.

The Journal of biological chemistry

Assembled pre-B cell receptor complexes are retained in the endoplasmic reticulum by a mechanism that is not selective for the pseudo-light chain.

09-08-1996

Clinical pharmacokinetics

Clinical pharmacokinetics of topotecan.

European journal of cancer (Oxford, England : 1990)

The toxicity of radiotherapy following high-dose chemotherapy with peripheral blood stem cell support in high-risk breast cancer: a preliminary analysis.

The Journal of experimental medicine

CD27 cooperates with the pre-T cell receptor in the regulation of murine T cell development.

Mechanisms of development

The Polycomb-group homolog Bmi-1 is a regulator of murine Hox gene expression.

Oncogene

Formation of Shc/Grb2- and Crk adaptor complexes containing tyrosine phosphorylated Cbl upon stimulation of the B-cell antigen receptor.

18-07-1996

Journal of the National Cancer Institute

Altered pharmacokinetics of vinblastine in Mdr1a P-glycoprotein-deficient Mice.

17-07-1996

Nucleic acids research

The telomeric GGGTTA repeats of Trypanosoma brucei contain the hypermodified base J in both strands.

Journal of cell science

Deficiency of the integrin beta 4 subunit in junctional epidermolysis bullosa with pyloric atresia: consequences for hemidesmosome formation and adhesion properties.

Cell adhesion and communication

Genomic organization of the mouse beta 1 gene: conservation of the beta 1D but not of the beta 1B and beta 1C integrin splice variants.

Nature genetics

Epithelial detachment due to absence of hemidesmosomes in integrin beta 4 null mice.

Biochimica et biophysica acta

Cell cycle regulation by the retinoblastoma family of growth inhibitory proteins.

07-06-1996

Journal of chromatography. B, Biomedical applications

Determination of polyoxyethyleneglycerol triricinoleate 35 (Cremophor EL) in plasma by pre-column derivatization and reversed-phase high-performance liquid chromatography.

07-06-1996

European journal of cancer (Oxford, England : 1990)

What have we learnt thus far from mice with disrupted P-glycoprotein genes?

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Palliative effect of metaiodobenzylguanidine in metastatic carcinoid tumors.

The Journal of clinical investigation

P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs.

Drug metabolism and disposition: the biological fate of chemicals

Isolation, purification and biological activity of major docetaxel metabolites from human feces.

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

A study of the reliability, validity and responsiveness of the HIV overview of problems evaluation system (HOPES) in assessing the quality of life of patients with AIDS and symptomatic HIV infection.

Oncogene

Oncogenic potential of a pre-T cell receptor lacking the TCR beta variable domain.

16-05-1996

Biochimica et biophysica acta

Retroviral insertional mutagenesis as a strategy to identify cancer genes.

16-05-1996

The EMBO journal

Sphingosine-1-phosphate rapidly induces Rho-dependent neurite retraction: action through a specific cell surface receptor.

15-05-1996

Cancer research

Nonlinear pharmacokinetics of paclitaxel in mice results from the pharmaceutical vehicle Cremophor EL.

01-05-1996

British journal of cancer

Efficacy of up-front 5-fluorouracil-epidoxorubicin-cyclophosphamide (FEC) chemotherapy with an increased dose of epidoxorubicin in high-risk breast cancer patients.

01-05-1996

The Journal of biological chemistry

Sos, Vav, and C3G participate in B cell receptor-induced signaling pathways and differentially associate with Shc-Grb2, Crk, and Crk-L adaptors.

12-04-1996

Molecular biology of the cell

A mechanism for inhibition of E-cadherin-mediated cell-cell adhesion by the membrane-associated mucin episialin/MUC1.

British journal of cancer

Pharmacokinetics and pharmacodynamics of carboplatin administered in a high-dose combination regimen with thiotepa, cyclophosphamide and peripheral stem cell support.

Current opinion in immunology

Composition and function of T-cell receptor and B-cell receptor complexes on precursor lymphocytes.

Trends in genetics : TIG

Cycling in Switzerland.

Annals of oncology : official journal of the European Society for Medical Oncology

Feasibility, psychometric performance, and stability across modes of administration of the CARES-SF.