Publications

Hereditary cancer in clinical practice

Withdrawal from genetic counselling for cancer.

15-02-2005

Molecular cell

The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway.

04-02-2005

Genes & development

PR72, a novel regulator of Wnt signaling required for Naked cuticle function.

01-02-2005

Nature medicine

The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk.

01-02-2005

Gastroenterology

Screening behavior of individuals at high risk for colorectal cancer.

01-02-2005

Cancer research

Comparative genomic hybridization profiles in human BRCA1 and BRCA2 breast tumors highlight differential sets of genomic aberrations.

01-02-2005

Nature cell biology

FoxM1 is required for execution of the mitotic programme and chromosome stability.

01-02-2005

European journal of cancer (Oxford, England : 1990)

Normal values of serum S-100B predict prolonged survival for stage IV melanoma patients.

01-02-2005

Clinical pharmacokinetics

Individualised cancer chemotherapy: strategies and performance of prospective studies on therapeutic drug monitoring with dose adaptation: a review.

20-01-2005

Rapid communications in mass spectrometry : RCM

Stable isotopically labeled internal standards in quantitative bioanalysis using liquid chromatography/mass spectrometry: necessity or not?

13-01-2005

Blood

Gene expression profiling in follicular lymphoma to assess clinical aggressiveness and to guide the choice of treatment.

01-01-2005

Cancer chemotherapy and pharmacology

Oral bioavailability of docetaxel in combination with OC144-093 (ONT-093).

01-01-2005

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

The insulin-like growth factor system in cancer prevention: potential of dietary intervention strategies.

01-01-2005

The Journal of biological chemistry

Ubiquitin ligase activity of c-Cbl guides the epidermal growth factor receptor into clathrin-coated pits by two distinct modes of Eps15 recruitment.

31-12-2004

Current biology : CB

Significant role for p16INK4a in p53-independent telomere-directed senescence.

29-12-2004

Nederlands tijdschrift voor geneeskunde

[New insights in the adjuvant treatment of gastric cancer].

18-12-2004

Mass spectrometry reviews

Liquid chromatography-mass spectrometry for the quantitative bioanalysis of anticancer drugs.

16-12-2004

Methods in molecular medicine

Gene transfer of MHC-restricted receptors.

09-12-2004

Methods in molecular biology (Clifton, N.J.)

Polo-like kinase-1: activity measurement and RNAi-mediated knockdown.

04-12-2004

European journal of cancer (Oxford, England : 1990)

The relevance of intraventricular chemotherapy for leptomeningeal metastasis in breast cancer: a randomised study.

01-12-2004

Journal of mass spectrometry : JMS

A simple and sensitive assay for the quantitative analysis of paclitaxel in human and mouse plasma and brain tumor tissue using coupled liquid chromatography and tandem mass spectrometry.

01-12-2004

Cancer cell

Oncogene addiction: sometimes a temporary slavery.

01-12-2004

EMBO reports

Detecting cAMP-induced Epac activation by fluorescence resonance energy transfer: Epac as a novel cAMP indicator.

01-12-2004

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy

Cancer cell death by programmed necrosis?

01-12-2004

Acta crystallographica. Section D, Biological crystallography

Towards complete validated models in the next generation of ARP/wARP.

01-12-2004

Rapid communications in mass spectrometry : RCM

Quantitative determination of the novel anticancer drug E7070 (indisulam) and its metabolite (1,4-benzenedisulphonamide) in human plasma, urine and faeces by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.

02-11-2004

Cell cycle (Georgetown, Tex.)

Checkpoint adaptation and recovery: back with Polo after the break.

01-11-2004

Medical physics

The long-term stability of amorphous silicon flat panel imaging devices for dosimetry purposes.

01-11-2004

British journal of cancer

A randomised phase II multicentre trial of irinotecan (CPT-11) using four different schedules in patients with metastatic colorectal cancer.

18-10-2004

The Journal of biological chemistry

ATP increases the affinity between MutS ATPase domains. Implications for ATP hydrolysis and conformational changes.

15-10-2004

The Journal of experimental medicine

The loss of PTEN allows TCR alphabeta lineage thymocytes to bypass IL-7 and Pre-TCR-mediated signaling.

04-10-2004

Journal of mass spectrometry : JMS

Quantitative analysis of the P-glycoprotein inhibitor Elacridar (GF120918) in human and dog plasma using liquid chromatography with tandem mass spectrometric detection.

01-10-2004

Journal of cell science

c-Cbl directs EGF receptors into an endocytic pathway that involves the ubiquitin-interacting motif of Eps15.

01-10-2004

Genes & development

Epigenetics and cancer.

01-10-2004

Molecular cell

Polo-like kinase-1 controls recovery from a G2 DNA damage-induced arrest in mammalian cells.

10-09-2004

Methods and findings in experimental and clinical pharmacology

Therapeutic drug monitoring of non-anticancer drugs in cancer patients.

01-09-2004

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

In vivo imaging of apoptosis by 99mTc-Annexin V scintigraphy: visual analysis in relation to treatment response.

01-09-2004

Clinical colorectal cancer

Topoisomerase I inhibitors in the treatment of gastrointestinal cancer: from intravenous to oral administration.

01-09-2004

The Journal of biological chemistry

Polo-like kinase-1 is required for bipolar spindle formation but is dispensable for anaphase promoting complex/Cdc20 activation and initiation of cytokinesis.

27-08-2004

Oncogene

Synergy of Nf2 and p53 mutations in development of malignant tumours of neural crest origin.

26-08-2004

Nature

Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB.

26-08-2004

Cell

Stem cells and cancer; the polycomb connection.

20-08-2004

Cancer research

Mechanism of the pharmacokinetic interaction between methotrexate and benzimidazoles: potential role for breast cancer resistance protein in clinical drug-drug interactions.

15-08-2004

Nucleic acids research

Structural analysis of the bipartite DNA-binding domain of Tc3 transposase bound to transposon DNA.

12-08-2004

Oncogene

Fgf10 is an oncogene activated by MMTV insertional mutagenesis in mouse mammary tumors and overexpressed in a subset of human breast carcinomas.

12-08-2004

Nature genetics

Mutagenic insertion and chromosome engineering resource (MICER)

01-08-2004

Cell death and differentiation

Mechanism of action of Drosophila Reaper in mammalian cells: Reaper globally inhibits protein synthesis and induces apoptosis independent of mitochondrial permeability.

01-08-2004

The Lancet. Oncology

Drug interactions in oncology.

01-08-2004

Cancer treatment reviews

Modulation of the blood-brain barrier in oncology: therapeutic opportunities for the treatment of brain tumours?

01-08-2004

Investigational new drugs

Efficacy of novel P-glycoprotein inhibitors to increase the oral uptake of paclitaxel in mice.

01-08-2004