Publications

Cancer chemotherapy and pharmacology

Absence of N-linked glycosylation does not affect plasma membrane localization of breast cancer resistance protein (BCRP/ABCG2).

01-10-2005

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Quality-of-life effects of prophylactic salpingo-oophorectomy versus gynecologic screening among women at increased risk of hereditary ovarian cancer.

01-10-2005

Investigational new drugs

Trabectedin (Yondelis, formerly ET-743), a mass balance study in patients with advanced cancer.

01-10-2005

Nederlands tijdschrift voor geneeskunde

[Rapid tracing of new patients with cancer through the nationwide network and registry of histo- and cytopathology in the Netherlands (PALGA) in order to freeze tumour material for molecular-epidemiological research].

01-10-2005

Cell cycle (Georgetown, Tex.)

p16INK4a as a second effector of the telomere damage pathway.

01-10-2005

Anti-cancer drugs

Phase I clinical and pharmacologic study of a 2-weekly administration of cisplatin and gemcitabine in patients with advanced non-small cell lung cancer.

01-10-2005

Cell

The human tumor antigen PRAME is a dominant repressor of retinoic acid receptor signaling.

23-09-2005

International journal of cancer

MRP2 (ABCC2) transports taxanes and confers paclitaxel resistance and both processes are stimulated by probenecid.

20-09-2005

Cancer research

Mice expressing a mammary gland-specific R270H mutation in the p53 tumor suppressor gene mimic human breast cancer development

15-09-2005

Menopause (New York, N.Y.)

Are cause of subfertility and in vitro fertilization treatment risk factors for an earlier start of menopause?

08-09-2005

EMBO reports

Ablation of the spindle assembly checkpoint by a compound targeting Mps1.

01-09-2005

Journal of pharmaceutical and biomedical analysis

Development and validation of an LC-UV method for the quantification and purity determination of the novel anticancer agent C1311 and its pharmaceutical dosage form.

01-09-2005

The oncologist

Current knowledge and future directions of the selective epidermal growth factor receptor inhibitors erlotinib (Tarceva) and gefitinib (Iressa).

01-09-2005

Stem cells (Dayton, Ohio)

Contribution of the ABC transporters Bcrp1 and Mdr1a/1b to the side population phenotype in mammary gland and bone marrow of mice.

01-09-2005

Cancer chemotherapy and pharmacology

Metabolism of docetaxel in mice.

01-09-2005

The oncologist

Development of farnesyl transferase inhibitors: a review.

01-09-2005

Cancer immunology, immunotherapy : CII

Prolonged low dose IL-2 and thalidomide in progressive metastatic renal cell carcinoma with concurrent radiotherapy to bone and/or soft tissue metastasis: a phase II study.

01-09-2005

Genome research

Genome-wide HP1 binding in Drosophila: developmental plasticity and genomic targeting signals.

01-09-2005

Nederlands tijdschrift voor geneeskunde

[Trends and variation in breast conserving surgery in the southeast and east of the Netherlands over the period 1990-2002].

27-08-2005

Cold Spring Harbor symposia on quantitative biology

Functional identification of cancer-relevant genes through large-scale RNA interference screens in mammalian cells.

25-08-2005

Cold Spring Harbor symposia on quantitative biology

Emerging roles of Polycomb silencing in X-inactivation and stem cell maintenance.

25-08-2005

Cancer research

The neurotrophic receptor TrkB in anoikis resistance and metastasis: a perspective.

15-08-2005

Nature

BRAFE600-associated senescence-like cell cycle arrest of human naevi.

04-08-2005

Molecular and cellular biology

p53-Dependent regulation of Cdc6 protein stability controls cellular proliferation.

01-08-2005

European journal of cancer (Oxford, England : 1990)

Effective palliation by low dose local radiotherapy for recurrent and/or chemotherapy refractory non-follicular lymphoma patients.

01-08-2005

Investigational new drugs

Human metabolism of [(14)C]indisulam following i.v. infusion in cancer patients.

01-08-2005

Investigational new drugs

Tumor and normal tissue pharmacokinetics of perifosine, an oral anti-cancer alkylphospholipid.

01-08-2005

Cell cycle (Georgetown, Tex.)

Re-evaluating the role of Frat in Wnt-signal transduction.

01-08-2005

Anti-cancer drugs

Compatibility and stability of Imexon in infusion devices and its in vitro biocompatibility.

01-08-2005

Current opinion in immunology

MHC multimer technology: current status and future prospects.

01-08-2005

Nature medicine

A rapid and potent DNA vaccination strategy defined by in vivo monitoring of antigen expression.

01-08-2005

Analytical and bioanalytical chemistry

Determination of oxaliplatin in human plasma and plasma ultrafiltrate by graphite-furnace atomic-absorption spectrometry.

01-08-2005

Journal of immunology (Baltimore, Md. : 1950)

During viral infection of the respiratory tract, CD27, 4-1BB, and OX40 collectively determine formation of CD8+ memory T cells and their capacity for secondary expansion.

01-08-2005

International journal of radiation oncology, biology, physics

Thymidine analogues to assess microperfusion in human tumors.

15-07-2005

The Journal of biological chemistry

Crystal structure of acetylcholine-binding protein from Bulinus truncatus reveals the conserved structural scaffold and sites of variation in nicotinic acetylcholine receptors.

15-07-2005

Journal of pharmaceutical and biomedical analysis

LC-UV method development and validation for the investigational anticancer agent imexon and identification of its degradation products.

15-07-2005

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Optimal locoregional treatment in gastric cancer.

10-07-2005

Rapid communications in mass spectrometry : RCM

Quantitative analysis of the farnesyl transferase inhibitor lonafarnib (Sarasartrade mark, SCH66336) in human plasma using high-performance liquid chromatography coupled with tandem mass spectrometry.

05-07-2005

Head & neck

Hypoxia in head and neck cancer: how much, how important?

01-07-2005

Drug metabolism and disposition: the biological fate of chemicals

Midazolam and cyclosporin a metabolism in transgenic mice with liver-specific expression of human CYP3A4.

01-07-2005

European journal of cancer (Oxford, England : 1990)

Standardised FDG uptake: a prognostic factor for inoperable non-small cell lung cancer.

01-07-2005

International journal of radiation oncology, biology, physics

Pulmonary function changes after radiotherapy in non-small-cell lung cancer patients with long-term disease-free survival.

01-07-2005

Cancer immunology, immunotherapy : CII

A phase-II study of pegylated interferon alfa-2b for patients with metastatic renal cell carcinoma and removal of the primary tumor.

01-07-2005

Nature structural & molecular biology

Crystal structure of nicotinic acetylcholine receptor homolog AChBP in complex with an alpha-conotoxin PnIA variant.

01-07-2005

Genome biology

Histone modifications: from genome-wide maps to functional insights.

18-06-2005

Cell

Stem cells for lung cancer?

17-06-2005

Cell

A genetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity.

17-06-2005

Genes & development

Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice.

15-06-2005

The Journal of biological chemistry

Modeling and experimental validation of the binary complex of the plectin actin-binding domain and the first pair of fibronectin type III (FNIII) domains of the beta4 integrin.

10-06-2005

The Journal of biological chemistry

Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate.

03-06-2005