Publications

Clinical pharmacokinetics

Genetic polymorphisms of drug-metabolising enzymes and drug transporters in the chemotherapeutic treatment of cancer.

03-03-2006

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

The significance of one positive axillary node.

01-03-2006

Clinical cancer research : an official journal of the American Association for Cancer Research

Radiosensitization of squamous cell carcinoma by the alkylphospholipid perifosine in cell culture and xenografts.

01-03-2006

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Relationship between cisplatin administration and the development of ototoxicity.

20-02-2006

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

The prognosis of patients with local recurrence more than five years after breast conservation therapy for invasive breast carcinoma.

01-02-2006

Medical physics

Accurate two-dimensional IMRT verification using a back-projection EPID dosimetry method.

01-02-2006

International journal of radiation oncology, biology, physics

Resistance of hypoxic cells to ionizing radiation is influenced by homologous recombination status.

01-02-2006

Nature medicine

Design and use of conditional MHC class I ligands.

01-02-2006

Biomedical chromatography : BMC

A rapid and simple HPLC-UV method for the determination of inhibition characteristics of farnesyl transferase inhibitors.

01-02-2006

The EMBO journal

Dual role of MutS glutamate 38 in DNA mismatch discrimination and in the authorization of repair.

25-01-2006

Clinical pharmacokinetics

Mass balance studies, with a focus on anticancer drugs.

25-01-2006

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Long-term risk of cardiovascular disease in 5-year survivors of testicular cancer.

20-01-2006

The EMBO journal

CLIP-170 facilitates the formation of kinetochore-microtubule attachments.

11-01-2006

The Journal of biological chemistry

The rac activator Tiam1 is a Wnt-responsive gene that modifies intestinal tumor development.

06-01-2006

Nature reviews. Cancer

Paradoxical roles of the immune system during cancer development.

01-01-2006

EMBO reports

Survivin mediates targeting of the chromosomal passenger complex to the centromere and midbody.

01-01-2006

Nature reviews. Cancer

KLF4, p21 and context-dependent opposing forces in cancer.

01-01-2006

Biomedical chromatography : BMC

A simple and sensitive assay for the quantitative analysis of paclitaxel and metabolites in human plasma using liquid chromatography/tandem mass spectrometry.

01-01-2006

Die Pharmazie

Compatibility and stability of the novel anticancer agent ES-285 x HCl formulated with 2-hydroxypropyl-beta-cyclodextrin in infusion devices.

01-01-2006

Trends in pharmacological sciences

Use of P-glycoprotein and BCRP inhibitors to improve oral bioavailability and CNS penetration of anticancer drugs.

01-01-2006

Trends in pharmacological sciences

The function of breast cancer resistance protein in epithelial barriers, stem cells and milk secretion of drugs and xenotoxins.

01-01-2006

Carcinogenesis

Breast cancer resistance protein (Bcrp1/Abcg2) reduces systemic exposure of the dietary carcinogens aflatoxin B1, IQ and Trp-P-1 but also mediates their secretion into breast milk.

01-01-2006

Nucleic acids research

Human and mouse oligonucleotide-based array CGH

16-12-2005

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Immunogenicity, including vitiligo, and feasibility of vaccination with autologous GM-CSF-transduced tumor cells in metastatic melanoma patients.

10-12-2005

Nucleic acids research

Rapid and quantitative detection of homologous and non-homologous recombination events using three oligonucleotide MLPA.

09-12-2005

The Journal of cell biology

Nesprin-3, a novel outer nuclear membrane protein, associates with the cytoskeletal linker protein plectin.

05-12-2005

The Journal of cell biology

The Rac activator Tiam1 is required for (alpha)3(beta)1-mediated laminin-5 deposition, cell spreading, and cell migration.

05-12-2005

Cell

A genomic and functional inventory of deubiquitinating enzymes.

02-12-2005

PDA journal of pharmaceutical science and technology

Pharmaceutical development of a parenteral lyophilised dosage form for the novel anticancer agent C1311.

01-12-2005

Molecular and cellular biology

Association of BMI1 with polycomb bodies is dynamic and requires PRC2/EZH2 and the maintenance DNA methyltransferase DNMT1.

01-12-2005

Trends in pharmacological sciences

An emerging role for PtdIns(4,5)P2-mediated signalling in human disease.

01-12-2005

Cancer cell

Mitogen requirement for cell cycle progression in the absence of pocket protein activity.

01-12-2005

Current gene therapy

Prospects and limitations of T cell receptor gene therapy.

01-12-2005

Cell cycle (Georgetown, Tex.)

CDK-dependent stabilization of Cdc6: linking growth and stress signals to activation of DNA replication.

01-12-2005

Cellular and molecular life sciences : CMLS

Dissection of cytotoxic and helper T cell responses.

01-12-2005

Therapeutic drug monitoring

Population pharmacokinetics of cyclophosphamide and its metabolites 4-hydroxycyclophosphamide, 2-dechloroethylcyclophosphamide, and phosphoramide mustard in a high-dose combination with Thiotepa and Carboplatin.

01-12-2005

British journal of cancer

Phase I and pharmacological study of the farnesyltransferase inhibitor tipifarnib (Zarnestra, R115777) in combination with gemcitabine and cisplatin in patients with advanced solid tumours.

28-11-2005

Oncogene

Retroviral insertional mutagenesis: past, present and future.

21-11-2005

Rapid communications in mass spectrometry : RCM

Simultaneous quantification of fludarabine and cyclophosphamide in human plasma by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.

16-11-2005

International journal of radiation oncology, biology, physics

Automatic prostate localization on cone-beam CT scans for high precision image-guided radiotherapy.

15-11-2005

Methods in enzymology

Functional annotation of deubiquitinating enzymes using RNA interference.

09-11-2005

Nature cell biology

The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene.

01-11-2005

The Journal of pharmacology and experimental therapeutics

Coformulated N-octanoyl-glucosylceramide improves cellular delivery and cytotoxicity of liposomal doxorubicin.

01-11-2005

European journal of cancer (Oxford, England : 1990)

Quality of life among long-term breast cancer survivors: a systematic review.

01-11-2005

Breast cancer research and treatment

Electrophysiological correlates of information processing in breast-cancer patients treated with adjuvant chemotherapy.

01-11-2005

Clinical pharmacokinetics

Clinical pharmacokinetics of cyclophosphamide.

20-10-2005

British journal of cancer

No common denominator for breast cancer lymph node metastasis.

17-10-2005

PDA journal of pharmaceutical science and technology

Pharmaceutical development of a parenteral lyophilised formulation of the investigational anticancer agent ES-285.HCl.

13-10-2005

Cancer investigation

Modulation of oral drug bioavailability: from preclinical mechanism to therapeutic application.

01-10-2005

Cancer chemotherapy and pharmacology

Aprepitant inhibits cyclophosphamide bioactivation and thiotepa metabolism.

01-10-2005