Margarida L. F. Martins

Margarida L. F. Martins

PhD student

+31 20 512 2096 Alfred Schinkel

I am currently studying different types of compounds, ranging from potent analgesics to potential anti-addiction agents and anti-cancer drugs. I am specifically interested in getting a better understanding of how membrane drug transporters and drug-metabolizing enzymes can have an impact on the tissue distribution and plasma exposure of those compounds. For that, we are making use of wild-type and genetically modified mouse models and cell lines, which have proved to be excellent tools to elucidate factors that affect both the safety and efficacy profiles of drugs.

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