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Salgado Polo, Fernando

Fernando Salgado Polo

Ph.D. student


I studied Biochemistry at the Complutense University of Madrid and completed my master's degree at the VU University Amsterdam. My work in Tassos Perrakis's lab focuses on two main projects:

- Characterizing the catalysis and allosteric modulation of the lysophospholipase Autotaxin (ATX), the main producer of the bioactive lipid lysophosphatidic  acid (LPA), as well as the mechanism by which ATX presents its product to the LPA receptors at the cell surface.

- Understanding the intracellular trafficking and ligand specificity of several members in the glycerophosphodiester phosphodiesterase (GDE) family, namely, GDE2 and GDE3, which recognize GPI-anchored proteins.