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Bas Pilzecker group

Pilzecke, Bas

Bas Pilzecker

Ph.D. Student

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Currently, I work on the translesion synthesis and more specifically PCNA K164R involvement in translesion synthesis and interaction with translesion synthesis polymerases. The K164R mutation leaves cells highly
sensitive to alkylating agents, therefore we are also exploring PCNA K164 ubiquitination inhibition as chemosensitization strategy. During my master Cancer Genomics and Developmental Biology in Utrecht, I did internships in the Korswagen lab at the Hubrecht Institute on C. elegans and Wnt signaling

I did my second intern in the Innocenti lab at the NKI/AVL, where I studied mDia2 in  filopodia formation.

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