This website uses cookies

This websites contains videos from YouTube. This company uses cookies (third party cookies). If you do not want them to use these cookies, you can indicate so here. However, this does mean that you will not be able to watch videos on this website. We also make use of our own cookies in order to improve our website. We don’t share our data with other parties. Read more about our cookie policy

This website uses cookies to enable video and to improve the user experience. If you do not want to accept these cookies, indicate so here. Read more about our cookie policy

Ga direct naar de inhoud, het hoofdmenu, het servicemenu of het zoekveld.

Back to overview
Paes Dias, Mariana

Mariana Paes Dias

Ph.D. Student

Experience

I graduated  in Cell and Molecular Biology (NOVA University of Lisbon, Portugal). Next, I obtained my Master's degree in Molecular Medicine and Oncology (University of  Porto, Portugal).

My PhD project aims to identify genes that confer resistance to synthetic lethality drugs in BRCA1/2-deficient tumour cells and to unveil molecular mechanisms leading to drug resistance. I will use cancer cell lines and organoids from genetically engineered mouse models of BRCA1- and BRCA2-deficient breast to conduct in vitro drug resistance screens with genome-wide and DNA damage response focused shRNA and CRISPR/Cas9 libraries.