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Andrea Murachelli

Postdoctoral Fellow


I am a structural biologist: I use bioinformatics, biochemistry and protein crystallography to determine the structure of protein complexes. This allows me to understand in detail how these complexes function in a healthy cell and how they fail in case of disease.

During my graduate studies, I investigated protein complexes involved in endocytosis, splicing and apoptosis.

In 2013 I started my postdoc in Titia Sixma's lab, working on the structure of complexes involved in ubiquitin conjugation and removal during DNA repair. From these structures I hope to better understand how ubiquitin signaling affects DNA repair and, possibly, cancer development.