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Wouter Moolenaar group

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Wouter Moolenaar

Group leader, professor

Personal details

Experience

Phospholipids are best known as the major building blocks of cell membranes, but some lipids play a signaling rather than a structural role. Our group is interested in nature's simplest phospholipid, lysophosphatidic acid (LPA), which we discovered as a lipid growth factor many years ago. Since then, our group has made substantial progress in unraveling how LPA regulates numerous biological processes, including cell migration and proliferation. Our current work focuses on the LPA-producing enzyme autotaxin, specifically its mechanism of action and role in tumor progression. Our ultimate goal is to translate new findings on autotaxin-LPA signaling into more effective anticancer strategies.

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