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Messal, Hendrik

Hendrik Messal

Postdoctoral fellow

Experience

I am a postdoc in Jacco van Rheenen's team where I explore the mechanisms that drive tissue remodeling in regeneration and cancer. My technical approach includes intravital microscopy, whole organ imaging, genetic interference, single-cell omics and mathematical modeling.

Before joining the NKI, I did my PhD at the Francis Crick Institute in London in the lab of Axel Behrens where I developed a technique for 3D whole organ microscopy.  I employed this technology to quantitatively describe tumour progression in the pancreas and uncovered a fundamental principle by which the local tissue geometry instructs adult tissue morphogenesis and modulates neoplasia biology.