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Jawahar Kopparam

Postdoctoral Fellow


I am interested in understanding the molecular mechanisms involved in cancer cell differentiation and metastasis. During my doctoral studies, I investigated factors regulating NF-kB and STAT3 pathways that contribute to lung adenocarcinoma development. This resulted in the identification of a protein kinase, RIP4, as a novel regulator of STAT3 pathway and hence lung adenocarcinoma differentiation. I am currently investigating the importance of polycomb proteins in the regulation of tumor heterogeneity found in small cell lung cancer.