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Marco Barazas group


Marco Barazas

Ph.D. Student

Personal details


"It is my goal to get a better understanding of the impact of inter- or intra-tumor heterogeneity on cancer therapy by studying genetically engineered mouse models for breast cancer. We found that escape mechanisms to classic chemotherapy or radiotherapy not only differ between individual tumors, but also between tumors derived from a unique donor tumor. Using next generation sequencing, proteomics and functional genetic screens, I focus on the question how these tumors have evolved upon therapy exposure and which escape mechanisms have been selected out. My hope is that this knowledge may be useful to improve cancer treatment."

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