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Tomasz Ahrends group

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Tomasz Ahrends

Ph.D. Student

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I studied biotechnology at the Intercollegiate Faculty of Biotechnology, University of Gdańsk, Poland. Following an internship at UCSF I started working on my PhD project at the NKI. In our lab we are studying the key molecular mechanisms that optimize cytotoxic CD8 T cell responses as a result of CD4 T cell help. We make use of an experimental model in which we administer DNA vaccines to mice and engage CD4 T-cell help or not. In this way, we can identify the contribution of CD4 T cell help, at which stage it needs to be delivered and what is the molecular mechanism underlying this help. Our findings are important for vaccination strategies against cancer and infectious disease.

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