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Members Postdoc Committee

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Jastrzebski, Kathy.jpg

Kathy Jastrzebski

Postdoctoral Fellow

Experience

I received my PhD from the University of Melbourne in 2008 and subsequently worked as a postdoctoral fellow at the Peter MacCallum Cancer Centre.

In 2011, I joined the group of Roderick Beijersbergen and my current work involves utilizing high throughput approaches in order to identify predictors of response to therapeutics in breast cancer.

 

 

 

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Petra van Houdt

Postdoctoral Fellow

Experience

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Van der Vos, Kristan

Kristan van der Vos

Postdoctoral Fellow

Experience

I obtained my PhD in the lab of Paul Coffer (Utrecht University) studying the PI3K-Akt-FOXO pathway. After graduating in 2010, I moved to Boston where I investigated the potential of circulating extracellular vesicles as a source of biomarkers in glioblastoma (Massachusetts General Hospital/Harvard Medical School).

In 2014 I joined the NKI to work under supervision of Michiel van der Heijden and René Bernards. My projects focus on understanding the emergence of therapy resistance in bladder cancer. We aim to identify prognostic biomarkers by epigenetic profiling and by analyzing the longitudinal kinetics of tumor mutations in biofluids.

 

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Cerutti, Aurora

Aurora Cerutti

Postdoctoral fellow

Experience

I obtained my PhD in Fabrizio d'Adda di Fagagna's lab, at IFOM in Milan, where I worked on oncogene-induced DNA damage and DNA replication stress, with particular focus on telomeres. Supported by EMBO short term fellowship, I spent few months at Genomic Vision, Paris, to learn DNA Molecular Combing, a cutting-edge technique to study DNA replication dynamics. I have been involved in various international collaborations related to replication stress at whole genome level and at telomeres. In Jacqueline Jacobs' lab, my aim is to better dissect the pathways and factors involved in telomere maintenance by focusing on telomere damage regulation, as well as telomere replication stress.

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Bosdriesz, Evert

Evert Bosdriesz

Postdoctoral Fellow

Experience

After I obtained my M.Sc in Theoretical Physics at the University of Amsterdam (cum laude), I decided to switch fields and did a PhD in Systems Biology at the Vrije Universiteit Amsterdam. There, my research focused on understanding cellular physiology from an evolutionary perspective.

My general research interest is in using theoretical and computational approaches to elucidate complex  biological systems.  At the Netherlands Cancer Institute, in collaboration with others, I work on signaling crosstalk in colon cancer, Our aim is to elucidate how signaling networks are rewired in response to targeted drug treatment, in order to rationally design combination therapies.

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Nedergaard, Andre

Arne Nedergaard Kousholt

Postdoctoral fellow

Experience

I work as a postdoc in the lab of Jos Jonkers, where I am using advanced mouse models to investigate a potential novel tumour suppressor for breast cancer. I will test if specific genetic changes can cause breast cancer, and using these models, I will study treatment response and drug resistance for these specific breast cancer subtypes. Moreover, I will setup an in-vitro assay for testing pathogenic roles of patient derived breast cancer mutations. I did my PhD under the supervision of associated professor Claus Storgaard Sørensen, BRIC, university of Copenhagen. My primary research experience lies within basic research in the field of the DNA Damage Response (DDR).

 

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Schepers, Arnout

Arnout Schepers

Potsdoctoral Fellow

Experience

I'm a postdoctoral scientist sponsored by a research fellowship from the Dutch Cancer Society (KWF). I'm interested in how tissues grow and maintain themselves, and how this is affected during disease, for example in cancer.

I did my PhD in the lab of Hans Clevers at the Hubrecht Institute, where my projects were primarily focused on the characterization of intestinal stem cells.

For the first part of my postdoctoral training, I worked on liver tissue engineering, microfluidics and enhancing the functionality of engineered tissue in the lab of Sangeeta Bhatia at the Koch Institute for Integrative Cancer Research at MIT.

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Jasper Nijkamp

Jasper Nijkamp

Senior Post doc

Experience

In 2004 I did my master internship medical informatics at the radiotherapy department of the NKI-AvL. The subject was setup error correction during radiotherapy. Subsequently, in 2005 I started working at the RT department in the Image-Guided Adaptive RT  group. The work was focused on clinical implementation of image-guidance solutions from the research. Topics I worked on were respiratory correlated CT scanning of lung tumors, and adaptive radiotherapy for prostate cancer. In 2009 I started on my PhD project titled (un-)certainties in radiotherapy of rectal cancer. Results of my research were new national guidelines in the definition of the target volume, and also novel safety margins for accurate radiotherapy.  In 2012 I made a switch to the surgery department of the NKI-AvL, to work on image-guided surgery. My main topic is surgical navigation for mobile tumors.

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Begona Diosdado

Pathologist, PhD

Experience

I am a pathologist interested in molecular biology of cancer and bringing basic science findings into clinical applications.

At present I am a Dutch Cancer Society Fellow interested in understanding the molecular pathogenesis of the described colorectal cancer molecular subtypes and the translation of these findings into targeted therapies. To translate the colorectal cancer genetic pathway additions into novel combination targeted therapies I will be making use of functional genetic screens and colorectal cancer 3D organoid models.

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Prekovic, Stefan

Stefan Prekovic

Postdoctoral Fellow

Experience

I obtained my master's degree in molecular genetics at the Centre for Human Molecular Genetics, University of Belgrade (Serbia). Following that, I moved to the Faculty of Medicine, KU Leuven (Belgium), where I did my doctoral training. The focus of my research there was the molecular biology of the androgenreceptor and resistance to antiandrogens in prostate cancer. After graduating in June 2017, I moved to Amsterdam (Netherlands) and started work as a postdoctoral fellow in the laboratory of Wilbert Zwart. My current research focuses on nuclear receptor genomics in non-endocrine cancers.

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Liqin Wang

Postdoctoral Fellow

Experience

For many cancer cases, mono-targeted drug therapy can work in the short term, but cancer often develops resistance mechanisms to escape the therapy and continue growing.

My research projects focus on identifying and studying the possible drug-resistance mechanisms that developed during mono-targeted cancer therapies. The outcome of the research can be used to develop better therapeutic approaches with alternative drug or drug combination that blocks the drug-resistance pathways and restore sensitivity to the original drug, in order to overcome drug resistance.

I hope that the knowledge that gained from my research projects can be translated from bench to clinic and benefits the cancer patients.

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Lorenzo Bombardelli

Lorenzo Bombardelli

Postdoctoral Fellow

Experience

I'm a researcher with extensive experience in oncology and biotechnology. Since my Ph.D (State University of New York at Stonybrook, 2008) I worked on cancer genetics, preclinical target validation and experimental therapies.

My current research focuses on understanding drug toxicity and developing methods to prevent it. Failures in late clinical trials are a burden for patients and companies and often undetectable in preclinical studies. My goal is to develop a high-throughput technology to precisely and quantitatively detect activations of liver toxicity-triggering pathways. Combining such technology with genetic screens will lead to the discovery of mechanisms to modulate and prevent toxicity.

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Trieu My Van

Trieu My Van

Postdoctoral fellow

Experience

I studied Biology at the University of Cologne, Germany and completed my PhD at the CECAD research Institute in Cologne in 2017. During my PhD I focused on deciphering the role of the immune response and cell death on HCC and lung cancer development. I continued as a PostDoc at the CECAD research Institute before I started my PostDoc in Christian Blank's group in April 2018.

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