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In 2013 I finished my Master in Pharmacy at Utrecht University.
In my master research project I studied the pleiotropic effects of
statins and ACE-inhibitors in patients with COPD at The University
of Alabama at Birmingham, United States. Thereafter, I worked as a
pharmacist in a hospital pharmacy. My projects focus on phase I/II
In 2012 I finished medical school at the University of Amsterdam
cum laude. During medical school I did an internship oncology at
the NKI. The first year after graduating I worked as a resident of
internal medicine in Flevo Hospital. Hereafter I entered a resident
training program to become an internist. The past eighteen months I
worked as a resident in internal medicine.
Due to increasing interest in research I decided to interrupt my
residency. During my PhD studies I will focus on phase I/II
clinical trials. My main focus will be the REVIVAL study of
carboplatin-olaparib in BRCAm breast cancer patients.
I studied medicine at VUmc. In July 2015 I obtained my master's
degree and started working as ANIOS oncology at the SLAZ hospital
for 9 months. My project in The Netherlands cancer institute
consists of phase I clinical studies with nivolumab in combination
with newer therapies.
I finished medical school at the University of Amsterdam in
january 2014. Hereafter I worked for 1 year as a resident in
internal medicine at the AvL/NKI and for 8 months in Spaarne
hospital. Due to my work in the clinic I became more and more
interested in research, especially in oncology. I focus on phase I
studies related to targeted therapy for BRAF mutated tumors.
I am involved as an independent researcher in the development
and validation of non-invasive predictive and pharmacodynamic
biomarker assays for monitoring the effect of molecular targeted
anticancer agents. These assays can be used to predict if a patient
will benefit from a particular treatment. This work includes: 1.
enzymatic activity assays for dihydropyrimidine dehydrogenase,
thymidine synthase, and polyADPribose polymerase. 2. assays for the
enumeration of circulating epithelial and melanoma tumor cells.
My name is Willeke Ros I have completed my bachelor in Biology
and my master in Biomedical Sciences at Leiden University. During
my studies I have performed various internships focusing
mostly on fundamental research questions. However, during my last
internship at the University of Wisconsin-Madison, I did research
which was part of clinical trials. I enjoyed the translational
nature of the research and decided I wanted to continue doing
clinical research. During my PhD studies I will focus on phase I/II
clinical trials related to immunotherapy.
I finished my master in Pharmacy in April 2018 and shortly
after started my PhD at the NKI-AVL. The main focus of my PhD will
be improving the safety, feasibility and cost-effectiveness of
genotype- and phenotype-directed individualized dosing of
Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data
(2015) Lancet Oncol. Oct 21. pii: S1470-2045(15)00286-7. doi: 10.1016/S1470-2045(15)00286-7. [Epub ahead of print]
Meulendijks D, Henricks LM, Sonke GS, Deenen MJ, Froehlich TK, Amstutz U, Largiadèr CR, Jennings BA, Marinaki AM, Sanderson JD, Kleibl et al.