Scientific seminars


The NKI frequently organizes seminars for which renowned national and international speakers are invited. These seminars are also open to scientists from outside the NKI-AVL.
Changes and cancellations are infrequent, but please check this page for updates.

seminars 2012 winter/spring

Seminars 2012

 

Thursday
Jan 12
Alfred Goldberg: New insights into proteasome function: From protein degradation to cancer therapy
Auditorium, 15.00 hrs; hosted by Huib Ovaa
Friday
Jan 13
Matthijs Verhage: The protein machines that regulate organelle docking & fusion and cargo delivery at the surface
Auditorium, 11.00 hrs; hosted by Peter Peters
Tuesday
Jan 17
Dirk Busch: Mechanisms of protection towards intracellular pathogens and it's implications for immunotherapy
Seminar room H8, 11.45 hrs; hosted by Ton Schumacher
Friday
Jan 20
Johannes Walter: The mechanism and regulation of DNA replication:  from cell-free systems to single molecules
Auditorium, 11.00 hrs; hosted by Linda Clijsters
Friday
Jan 27
Marcus Groettrup: How, where, and why the ubiquitin-like modifier FAT10 targets substrates for degradation by the proteasome
Auditorium, 11.00 hrs; hosted by Huib Ovaa
Monday
Jan 30
Ruth Sperling: A novel quality control mechanism that regulates alternative 5’ splice site selection
Room Z4, 15.00 hrs; hosted by Reuven Agami
Friday
Feb 3
Clemens Schmitt: Senescence and senescence-related vulnerabilities in cancer therapy
Auditorium, 11.00 hrs; hosted by Christian Blank
Thursday
Feb 9
Siewert-Jan Marrink: Across the membrane: insights obtained by computational microscopy
Room Z4, 15.00 hrs; hosted by Albert van Hell
Friday
Feb 17
Daniel Durocher: Chromatin ubiquitylation and the response to DNA double-strand breaks
Auditorium, 11.00 hrs; hosted by Jacqueline Jacobs
Friday
Mar 2
Lodewyk Wessels: Molecular networks in cancer
Auditorium, 11.00 hrs
Friday
Mar 9
CANCELLED James Bradner: Chemical inhibition of bromodomains
Auditorium, 11.00 hrs; hosted by Jan-Hermen Dannenberg
Friday
Mar 16
Peter Lansdorp: Studies of genomic (re-) arrangements in single cells by analysis of DNA template strands
Auditorium, 11.00 hrs; hosted by Jacqueline Jacobs
Friday
Mar 23
Paul Nurse: Controlling the cell cycle
Auditorium, 11.00 hrs; hosted by Rob Wolthuis
Monday
April 2
Hiroshi Ohno: Function and development of specialized epithelial cells, M cells
Room Z4, 16.00 hrs; hosted by Peter Peters
Friday
Apr 13
Andreas Trumpp: Dormant blood stem cells and circulating cancer stem cells 
Auditorium, 11.00 hrs; hosted by Piet Borst
Tuesday
Apr 24
Lars Zender: Oncogenomics-based approaches to unravel liver cancer
Auditorium, 11.00 hrs; hosted by Daniel Peeper
Friday
Apr 27
Mike Hemann: Using mouse models to improve cancer therapy
Auditorium, 11.00 hrs; hosted by Daniel Peeper
Friday
May 4
Antoine van Oijen: Under the hood: Single-molecule studies of DNA replication
Auditorium, 11.00 hrs; hosted by Peter Peters
Friday
May 11
Giorgio Scita: Membrane and actin dynamics in the plasticity of tumor cell migration
Auditorium, 11.00 hrs; hosted by Metello Innocenti
Friday
May 25
Stefano Piccolo: On the molecular nature of breast cancer stem cells
Auditorium, 11.00 hrs; hosted by Reuven Agami
Friday
June 7
Douglas Hanahan: Multi-factoral determinants of malignant progression
Auditorium, 15.00 hrs; hosted by ISPCC - Michiel Boekhout
DATE AND TIME ARE NOT FINAL - PLEASE CHECK WEBSITE
Friday
Jun 22
Johannes Zuber: Finding and probing cancer drug targets using advanced in-vivo RNAi
Auditorium, 11.00 hrs; hosted by Thijn Brummelkamp
Friday
July 6
Richard Gardner: How disorder prevents disaster in nuclear protein homeostasis
Auditorium, 11.00 hrs; hosted by Fred van Leeuwen

If you have questions about listed seminars, wish to propose a seminar speaker, or if you wish to be added or removed from the seminar mailing list, please contact:
Suzanne Corsetto, telephone: +31 20 512 1970
Email: s.corsetto@nki.nl

The scientific seminars program is under the supervision of the Seminar Committee (Reuven Agami, Fred van Leeuwen, Rob Wolthuis, Christian Blank, Jelle Wesseling and Suzanne Corsetto). The Seminar Committee organizes the Friday 11 o’clock seminars and occasionally seminars at other moments.

Seminars 2011

David Adams: Finding and validating cancer genes in the mouse
Jean-Christophe Andrau: From enhancer of transcription to enhancer transcription
Avi Ashkenazi: Pro-apoptotic receptor agonists as a strategy for cancer therapy
Keith Baggerly: The importance of reproducibility in high-throughput biology: case studies in forensic bioinformatics
David Barford: Structural basis for the subunit assembly of the anaphase promoting complex
Amy Berrington de Gonzalez: Projected cancer risks from current levels of diagnostic radiation exposure
Cedric Blanpain: Stem cells and skin cancers
Sandeep Burma: DNA double-strand break repair and the glioblastoma connection
Jason Carroll: Estrogen receptor genomics
Young-Tae Chang: Development of bioimaging probes for in vitro, in vivo and clinical applications by Diversity Oriented Fluorescence Library Approach (DOFLA)
Hans Clevers: Wnt signaling, Lgr5 stem cells and cancer
Gerald Cohen: Bcl-2 family, function and targeting
Steve Elledge: Adventures in human genetics
Wolfram Goessling: Fishing for novel regulators of liver development and cancer
Eyal Gottlieb: Metabolism controls cell fated
Piet Gros: Molecular mechanisms underlying complement activation and regulation
Robert Grosse: Signal regulation of Formin-mediated actin assembly
Nir Hacohen: Reconstructing circuits of the innate immune system
Ron Heeren: Pathway Imaging Mass Spectrometry: Multiplexed label-free detection of molecular signals on biological surfaces
Uulke van der Heide: Application of MRI in radiotherapy for tumor delineation and characterization
Phil Hodgkin: Tracking clonal cell division, death and differentiation fates reveals a statistical model for the cell
David Holden: Exploitation of mammalian cells by Salmonella
Nancy Hynes: Targeting signaling pathways in breast cancer
Peter Jones: The cancer epigenome
Jan Karlseder: Telomere function and dysfunction during the cell cycle
Jan Korbel: Detecting large-scale genetic variations in humans with second generation sequencing data
Paul Lehner: Viral regulation of plasma membrane proteins; new approaches to dissect host-pathogen interactions
Gustavo Leone: Pten and p53 pathways in the tumor microenvironment
René van Lier: With a little help of co-stimulation: selection of (sub)dominant T cell clones during immune reactions
Sabine Linn: Outlooks for treatment of breast cancer
Vivek Malhotra: Mechanism of protein secretion: conventional and unconventional
Michael Marks: Lysosome-related organelle biogenesis: What do dendritic cells and pigment cells have in common?
Jean-Claude Martinou: Membrane remodeling by Bcl-2 family members to trigger apoptosis
Maria Masucci: Highjacking of Ub and UbL signaling in Epstein-barr virus infection
Ultan McDermott: The genomics of drug sensitivity in cancer
Pascal Meier: Caspase activation and inhibitor of apoptosis proteins
Andrew Mouland: At the crossroads: Expanding roles of endosomal membranes in infectious disease and cancer
Patricia Muller: Mutant p53 drives RCP-mediated recycling of integrins and growth factor receptors to enhance invasion Lorenza Penengo: Ubiquitination and genome stability: how the ubiquitin ligase RNF168 regulates the DNA damage response
Roland Rad: Cancer gene discovery in mice using PiggyBac transposon mutagenesis
Carlos Reis: Computational design of TNF ligands
Antoni Ribas: TCR engineering and BRAF targeted therapy for melanoma
Kevin Ryan: Autophagy in cell death and cancer
Ton Schumacher: Dissecting T cell immunity in mice and men
Yosef Shaul: Mechanisms and metabolic regulation of protein degradation by default
Yang Shi: Histone methylation dynamics: mechanisms and link to human disease
Jane Skok: Chromosome dynamics in immune regulation
Quentin Smith: Improving drug delivery to brain for the treatment of brain metastases of breast cancer
Fraser Symmans: Developing, testing and implementing molecular approaches to tailor treatment of breast cancer patients
Shunichi Takeda: Analysis of DNA damage response using the chicken DT40 cell line
Stavros Taraviras: Differential role of Geminin in progenitor T cells and haematopoietic stem cells
Roman Thomas: Lung cancer genomics
Marc Timmers: Dynamic regulation of transcription and chromatin
Frank Uhlmann: Temporal ordering of progression through cell division
Peter Vandenabeele: Cutting both ways: How caspases promote and prevent cell death
Ashok Venkitaraman: Chromosome stability mechanisms in tumor suppression and cancer therapy
Peter Verrijzer: Undercover transcription factors in development and disease
Rob Wolthuis: Mechanisms of Cell Division: the Be All and the End All
Jerry Workman: Protein complexes that modify chromatin for transcription

 

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