News archive 2007

New mouse model for analysis of chemotherapy resistance in breast cancer

Researchers at the Netherlands Cancer Institute – Antoni van Leeuwenhoek Hospital have developed a new tumor model in mice that makes it possible to determine how a hereditary form of breast cancer becomes resistant to many of the anti-cancer drugs now being used.

Analysis of modified DNA base J and J-binding proteins in Leishmania

On Tuesday, July 3th, 2007 Paul-André Genest will defend his thesis titled “Analysis of the modified DNA base J and the J-binding proteins in Leishmania”.

Escape mechanism for pathogenic Mycobacteria

Tuberculosis and leprosy bacteria follow a different path into the host cell than that which for forty years scientists had always maintained. The insight has huge implications for an understanding of these diseases and for more effective medicines to combat TB, leprosy and even cervical cancer.

Honorary doctorate for Prof Piet Borst

Prof. Piet Borst will receive a honorary doctorate from the University of Dundee on Friday June 22nd.

René Bernards member Academy

Prof. dr. René Bernards, professor Molecular Carcinogenesis at the Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital was has been selected as a member of the Royal Netherlands Academy of Arts and Sciences (KNAW).

Honorary CBE awarded to Prof Piet Borst

Prof Piet Borst has been awarded an honorary CBE by Her Majesty The Queen for his outstanding contribution to UK and global science, especially in the field of cancer research.

Hunting novel cancer genes with an old tool

On 5 April, 12:00 h Vasso Theodorou will defend his PhD thesis on MMTV insertional mutagensis in mouse mammary tumors: hunting novel cancer genes with an old tool

High dose radiotherapy in lung cancer well tolerated and effective

Jose Belderbos has discovred that a new treatment scheme of radiotherapy given concurrently with daily chemotherapy was well tolerated in lung cancer patients. She will defend her PhD thesis on March 28.

Infectious activation drives cell division

Once active, the enzyme Cyclin B1-Cdk1 commits a growing cell to the process of mitotic cell division and chromosome separation, researchers of the NKI-AVL report in PLoS Biology.

On radiotherapy dose verification with a flat-panel imager

On 27 March Leah McDermott will defend her PhD thesis on radiotherapy dose verification with a flat panel imager, also known as an electronic portal imaging device.

17 novel candidate breast cancer genes

Scientists at the NKI-AVL have discovered 17 novel genes that are likely to play a role in breast cancer development. The work was published on line this week in Nature Genetics.

Appointment Professor Maarten van Lohuizen

Maarten van Lohuizen has been appointed as professor of Biology and Epigenetic regulation of Normal and Cancerous Stemcells at the University of Amsterdam, effective April 1

New minister of science in Science

Torn between two ladders

Should you stay in academia, on the bench or even quit science? Read about changing the focus on your career in Nature’s Career View by former NKI-AVL employee Alexander Griekspoor.

Optimizing Target Definition for Radiotherapy

On Wednesday January 31st Roel Steenbakkers of the department of Radiotherapy at the Netherlands Cancer Institute – Antoni van Leeuwenhoek Hospital, will defend his PhD thesis.

Dr. Josef Steiner Cancer Award 2007 for Reuven Agami

Rueven Agami has won the award for his project "Identification and characterization of micro RNAs with the capacity to affect tumor growth and responsiveness to therapy".

EMBO welcomes fifty leading scientists

Reuven Agami receives Dr. Josef Steiner Cancer Research Award 2007

Friday November 2th, Dr. Reuven Agami receives the Dr. Josef Steiner Cancer Award 2007 for his project "Identification and characterization of micro RNAs with the capacity to affect tumor growth and responsiveness to therapy".

Breast Cancer Research Foundation Award for Laura van 't Veer

PhD thesis defence F Hoebers

In this thesis, a number of studies are presented that aimed at applying or developing prognostic and predictive tests in order to be able to improve the (future) selection of patients for the appropriate treatment.

Lifetime Achievement Award to researchers NKI-AVL

The Netherlands Cancer Institute (NKI) is the winner of the second edition of the European Society for Medical Oncology (ESMO) Lifetime Achievement Award.

p15 critical tumour suppressor in absence of p16

Scientist at the Netherlands Cancer Institute – Antoni Van Leeuwenhoek Hospital in Amsterdam have discovered that p15 can fulfil a critical backup function for p16 and provide an explanation for the frequent loss of p16, p19 and p15 in human tumours.

A novel family of antibiotics

Researchers have discovered new ways to fight bacterial infections including extensively drug-resistant tuberculosis. The work will be published in the journal Nature on 29 November.

Increased cure of breast cancer with extra boost irradiation after surgery

A large European study shows that an extra “boost dose” of irradiation after surgery for breast cancer improves the chance of cure.